Planning for the Future: Why VZV Immunity Matters Before Pregnancy
Preparing for a baby is an exciting time, filled with planning and anticipation. Amidst the discussions about nursery colours and baby names, it is crucial not to overlook the importance of pre-conception health. One vital aspect of this preparation is understanding your immunity to certain infectious diseases, including the varicella zoster virus (VZV), the virus that causes chickenpox. Knowing your VZV immune status before pregnancy can help you protect both your health and the health of your future child.
The Risks of Chickenpox During Pregnancy
While chickenpox is typically a mild illness in childhood, it can be significantly more serious when contracted during adulthood, and particularly during pregnancy. Pregnant women who develop a primary VZV infection are at an increased risk of severe complications, such as varicella pneumonia, which can be life-threatening. [1]
Furthermore, the virus can be transmitted to the developing baby. If a mother contracts chickenpox during the first 28 weeks of pregnancy, there is a small risk of the baby developing foetal varicella syndrome (FVS). FVS can cause serious abnormalities, including skin scarring, eye defects, neurological issues, and shortened limbs. [2] If the mother develops chickenpox around the time of delivery, the newborn is at risk of severe neonatal varicella, which requires urgent medical intervention. [3]
The Importance of Pre-Conception Testing
Given these potential risks, the ideal time to address VZV immunity is before you become pregnant. For women who have a clear history of chickenpox, immunity can usually be inferred. However, for those who are unsure of their history or who grew up in countries where chickenpox is less common, confirming immunity is a sensible precaution.
A VZV IgG blood test can determine whether you have the necessary antibodies to protect against the virus. If the test reveals that you are not immune, you have the opportunity to discuss vaccination with your healthcare provider before trying to conceive. The varicella vaccine is a live vaccine and cannot be given during pregnancy, making pre-conception planning essential. [1]
Managing Exposure During Pregnancy
If you are already pregnant and do not know your immune status, it is important to be vigilant. If you come into contact with someone who has chickenpox or shingles, you should contact your GP or midwife immediately. They can arrange for an urgent VZV IgG blood test to check your immunity.
According to UK Health Security Agency (UKHSA) guidelines, if a susceptible pregnant woman has a significant exposure to VZV, post-exposure prophylaxis (PEP), such as antiviral medication, may be recommended to reduce the risk of severe disease. [3] Timely testing and intervention are crucial in these situations.
Empowering Your Pregnancy Journey with Clinilabs
Taking proactive steps to understand your health before pregnancy can provide invaluable peace of mind. By confirming your immunity to VZV, you can eliminate one potential source of worry and focus on a healthy, happy pregnancy.
The Varicella Zoster Virus IgG Blood Test from Clinilabs can form part of a proactive approach to your pre-conception health planning. This simple test can help provide insight into your immune status, allowing you to make informed decisions and discuss any necessary precautions with your healthcare professional. Empower yourself with knowledge and take control of your health journey.
Explore this topic
Continue reading the related articles in this series:
- Overview: Understanding Your Immunity: The Essential Guide to Varicella Zoster Virus
- Personalised insights: Protecting the Vulnerable: VZV Immunity and Immunosuppression
- Empowerment: Occupational Health: Why Healthcare Workers Need to Know Their VZV Status
Related test: Varicella Zoster Virus IgG Blood Test at Clinilabs.
References
[1] NHS. (2023). Chickenpox in pregnancy. https://www.nhs.uk/pregnancy/keeping-well/chickenpox/
[2] Royal College of Obstetricians and Gynaecologists (RCOG). (2015). Chickenpox in Pregnancy (Green-top Guideline No. 13). https://www.rcog.org.uk/guidance/browse-all-guidance/green-top-guidelines/chickenpox-in-pregnancy-green-top-guideline-no-13/
[3] UK Health Security Agency. (2025). Guidelines on post-exposure prophylaxis (PEP) for varicella or shingles. https://www.gov.uk/government/publications/post-exposure-prophylaxis-for-chickenpox-and-shingles/guidelines-on-post-exposure-prophylaxis-pep-for-varicella-or-shingles-january-2023